pretickt

Is TWST a good stock to buy?

Twist Bioscience Corporation · end-of-day data as of Nov 13, 2026

Twist Bioscience
TWST · $7.35B
$111.60-2.3%
Nov 13, 2026 · close
$150$200SepOctNov9:3016:003 months -3.9%Nov 13 · close
▲ 3
  • PT$145.70 +30.6%
  • ConsensusBuy · 13
  • Sector▲ +15.9%
Neutral
  • Earnings in80d
  • RSI38
  • Support-50.2%
  • Resistance+55.4%
  • Off 52w high-49.2%
  • Volume0.8x
  • Bollingerlower half
  • News1.00
  • Trendsideways
  • 52w range$23–$220
  • ATR+15.1%
  • Off ATH-49.2%
▼ 4
  • Insiders-$99.86M
  • MAs1 of 4
  • MA20×50Death 9d ago
  • MACD-3.21

Updates with the 15-min delayed price. Not a forecast or investment advice.

Is Twist Bioscience a good stock to buy?

Twist Bioscience is strong on 2 of the 5 questions about the business; weak on advantage, economics and execution. With a loss over the last 12 months, Twist Bioscience has no P/E ratio (Nov 13, 2026). pretickt does not say whether to buy or sell.

  1. Demand growing
  2. Advantage easy to copy
  3. Economics losing money
  4. Execution misses
  5. Fragility sturdy
  6. Price like its peers
DemandDo people want more of what it sells?growing

TWST sales growth revenue growth

+23%a year, for the last 3 years

Twist Bioscience's sales grew 23% a year for 3 years, to $459M in fiscal 2026.

TWST analysts' forecast revenue estimates

+19%the sales they expect next fiscal year, on the last

Analysts expect Twist Bioscience's sales to grow 19% to $549M in fiscal 2027 (8 analysts).

TWST competitors

pretickt analysis+22%its sales in 12 months, on a year before

Twist Bioscience's sales grew 22% in the 12 months to Sep 30, 2026, faster than Bio-Techne (+1%) and CRISPR Therapeutics (-33%), slower than Alnylam (+56%) and Incyte (+25%).

TWST sales by business revenue by segment

55%of its sales from Ngs Tools

Ngs Tools brought Twist Bioscience 55% of its sales in fiscal 2025; Synthetic Genes 30%.

Advantage moatIs it hard to copy?easy to copy

TWST return on capital ROIC

pretickt analysis-31%earned before tax on the money invested in it

Twist Bioscience earned -31% before tax on the capital invested in it in the 12 months to Sep 30, 2026; Alnylam 31%, Incyte 29%, Bio-Techne 11% and CRISPR Therapeutics -24%.

TWST margin on each sale gross margin

52%left after making the product

Twist Bioscience kept 52% of each sale after making the product in the 12 months to Sep 30, 2026; its competitors' median is 72%.

EconomicsDoes it make good money?losing money

TWST margin after costs profit margin

-30%of sales left after running the business

Twist Bioscience's operating margin was -30% in the 12 months to Sep 30, 2026, against -89% in fiscal 2023.

ExecutionDoes it deliver what it promises?misses

TWST earnings vs estimates

3 of 6quarters above the analysts' estimate

Twist Bioscience beat the analysts' profit estimate in 3 of 6 quarters, the latest on Aug 3, 2026; 2 quarters the sources disagree on are left out.

TWST insider selling

-$148Msold, net, by its executives in 12 months

Twist Bioscience's executives and directors sold a net $148M of shares in the 12 months to Nov 13, 2026; none bought.

TWST number of employees

+6%more people in a year

Twist Bioscience had 979 employees at the end of fiscal 2025, 6% more than a year before.

TWST CEO pay

$13.78Mfor fiscal 2025, 87% of it in stock and options

Twist Bioscience paid its CEO $13.78M for fiscal 2025, 87% of it in stock and options.

Fragility risksCould something break it?sturdy

TWST financial health Altman Z-score

20.0Altman Z-score, safe above 3

Twist Bioscience's Altman Z-score is 20.0 (Nov 13, 2026), above 3, where the safe zone starts.

Price valuationIs the price reasonable?like its peers

TWST price vs profit P/E ratio

—it lost money in 12 months: no P/E

Twist Bioscience has no P/E ratio: it lost money over the 12 months to Sep 30, 2026.

TWST price vs assets price to book

8.3×times what its assets are worth on paper

Twist Bioscience trades at 8.3 times its book value (Nov 13, 2026); its competitors' median is 4.8.

TWST analysts' target price target

+31%to their average target

Analysts' average price target for Twist Bioscience is $146, 31% above the Nov 13, 2026 close of $111.60.

What is Twist Bioscience's P/E ratio?

Twist Bioscience has no P/E ratio: it lost money over the 12 months to Sep 30, 2026. Twist Bioscience trades at 8.3 times its book value (Nov 13, 2026); its competitors' median is 4.8.

Who are Twist Bioscience's biggest competitors?

pretickt compares Twist Bioscience with Bio-Techne, CRISPR Therapeutics, Alnylam and Incyte. Twist Bioscience's sales grew 22% in the 12 months to Sep 30, 2026, faster than Bio-Techne (+1%) and CRISPR Therapeutics (-33%), slower than Alnylam (+56%) and Incyte (+25%).

Is Twist Bioscience profitable?

Twist Bioscience's operating margin was -30% in the 12 months to Sep 30, 2026, against -89% in fiscal 2023.

Who is dumping Twist Bioscience stock?

Twist Bioscience's executives and directors sold a net $148M of shares in the 12 months to Nov 13, 2026; none bought.

How does Twist Bioscience make money?

Ngs Tools brought Twist Bioscience 55% of its sales in fiscal 2025; Synthetic Genes 30%.

How many employees does Twist Bioscience have?

Twist Bioscience had 979 employees at the end of fiscal 2025, 6% more than a year before.

From the companies' statements (FMP), their filings read by pretickt, the analysts and the insiders, as of Nov 13, 2026. Each card says what a fact means for its question, never what to do with the stock: for information only, not investment advice.